Two long-distance Amtrak routes run through the state: California Zephyr: One of Amtrak’s most scenic and popular routes, traveling from Chicago to Emeryville, CA (near San Francisco), with stops in Burlington, Mount Pleasant, Ottumwa, Osceola, and Creston. Southwest Chief: Running between Chicago and Los Angeles, this line makes a single Iowa stop in Fort Madison. Combined, ... https://amtrak-station.com/stations/iowa-amtrak-stations/